How do I connect points to lines?

I have two data sets: One is a set of line segments from a DXF file. The other is a set of points created by importing a CSV text file with coordinates as well as a point ID. I want to link them to create an "old fashioned" GIS line topology where the attributes for each line segment include a "FromPointID" and "ToPointID" attribute that links to the Point Data.

The end goal of this exercise is to create multiple versions of the lines for further analysis by using different sets of points - each containing slightly different coordinates.

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